I would have a video games store, or a place that sold comics, manga, action figures, and games. I would even have a 'adult' section with hentai/yuri/yaoi, and some 'interactive toys' in the back and check ID. It would be cosplay friendly; and if there was demand for it I would have a lounge area where people could go hang-out...with game systems...and maybe karaoke....and board games.

I might just do that someday as the idea has made me giddy >.> but it would cost too much to start alone....